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葡萄糖酸鋅(Zinc Gluconate):血液透析患者的潛在必要補(bǔ)充劑

發(fā)表時(shí)間:2025-06-14 18:49

血液透析患者存在以下一些問(wèn)題:血清白蛋白水平下降、睡眠質(zhì)量差和生活質(zhì)量低下。由于血液透析期間血清白蛋白排泄增加,血液透析患者的血清白蛋白通常比健康個(gè)體少。此外,血液透析患者的高度炎癥和營(yíng)養(yǎng)不良會(huì)導(dǎo)致血清白蛋白合成減少。在改善血清白蛋白水平上,鋅元素對(duì)白蛋白合成過(guò)程至關(guān)重要。研究表明,補(bǔ)充鋅可促進(jìn)蛋白質(zhì)合成相關(guān)酶的活性,在嚴(yán)重鋅缺乏人群中,補(bǔ)充葡萄糖酸鋅(Zinc Gluconate)能顯著提升白蛋白水平;同時(shí),在糖尿病患者中,鋅元素還能減少血清白蛋白流失,這為血液透析患者提高血清白蛋白水平帶來(lái)希望。此外,鋅狀態(tài)與炎癥反應(yīng)密切相關(guān)。輕度鋅缺乏會(huì)促使單核細(xì)胞生成白細(xì)胞介素 1β(IL-1β)等促炎標(biāo)志物增加,而補(bǔ)充鋅可調(diào)節(jié)炎癥反應(yīng),降低 C 反應(yīng)蛋白(CRP)等炎癥指標(biāo)水平,減輕患者體內(nèi)炎癥狀態(tài),間接為血清白蛋白合成創(chuàng)造良好環(huán)境。且葡萄糖酸鋅Zinc Gluconate這種類型的鋅補(bǔ)充劑胃腸道吸收較好,消化不良事件較少,是血液透析患者的潛在必要補(bǔ)充劑。

葡萄糖酸鋅(Zinc Gluconate):血液透析患者的潛在必要補(bǔ)充劑

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抗壞血酸錳Manganese Ascorbate、抗壞血酸亞鐵Ferrous Ascorbate、賴氨酸甘氨酸鎂Magnesium Lysinate Glycinate、甘氨酸谷氨酰胺鎂Magnesium Glycinate Glutamine、檸檬酸蘋果酸鎂Magnesium Citrate Malate、檸檬酸鍶Strontium Citrate、檸檬酸錳Manganese Citrate、檸檬酸銅Copper Citrate、天門冬氨酸鋰Lithium Aspartate、?;撬嵛?/span>Selenium Taurate.

Zinc Gluconate: A Potential Essential Supplement for Hemodialysis Patients

Hemodialysis patients face several problems, such as decreased serum albumin levels, poor sleep quality, and low quality of life. Due to increased excretion of serum albumin during hemodialysis, the serum albumin level in hemodialysis patients is usually lower than that in healthy individuals. In addition, the high - level inflammation and malnutrition in hemodialysis patients lead to a reduction in serum albumin synthesis.In terms of improving serum albumin levels, zinc is crucial for the albumin synthesis process. Studies have shown that zinc supplementation can enhance the activity of enzymes related to protein synthesis. In people with severe zinc deficiency, supplementation with Zinc Gluconate can significantly increase albumin levels. Meanwhile, in diabetic patients, zinc can reduce the loss of serum albumin, which brings hope for hemodialysis patients to increase their serum albumin levels. Moreover, the zinc status is closely related to the inflammatory response. Mild zinc deficiency can prompt monocytes to increase the production of pro - inflammatory markers such as interleukin 1 beta (IL - 1β), while zinc supplementation can regulate the inflammatory response, reduce the levels of inflammatory indicators such as C - reactive protein (CRP), alleviate the inflammatory state in patients, and indirectly create a favorable environment for serum albumin synthesis.

Zinc supplements in the form of Zinc Gluconate are well - absorbed by the gastrointestinal tract and are associated with fewer indigestion events, making them a potential essential supplement for hemodialysis patients.

Zinc Gluconate: A Potential Essential Supplement for Hemodialysis Patients

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Magnesium Ascorbate, Magnesium Ascorbate, Magnesium Taurate, Zinc Amino Acids Chelate, Magnesium Amino Acids Chelate, Magnesium Orotate, Calcium Orotate, Calcium Succinate, Magnesium Succinate, Lithium Ascorbate.