檸檬酸蘋果酸鈣（Calcium Citrate Malate，CCM）對人體的影響

檸檬酸蘋果酸鈣（Calcium Citrate Malate，CCM），是鈣、檸檬酸和蘋果酸按一定比例合成的具有空間立體結(jié)構(gòu)的有機螯合物，機體對其鈣元素具有高吸收利用性。檸檬酸-蘋果酸鈣復(fù)合鹽具有較好的溶解性、高吸收利用性、風(fēng)味好等優(yōu)點，是一種理想的鈣營養(yǎng)強化劑。檸檬酸蘋果酸鈣的鈣吸收利用率比碳酸鈣高37% ，動物試驗也證明檸檬酸蘋果酸鈣生物活性要顯著高于碳酸鈣，機體對檸檬酸蘋果酸鈣中的鈣元素的吸收利用率和存留率比碳酸鈣更高。檸檬酸-蘋果酸鈣復(fù)合鹽之所以具有高吸收利用性，據(jù)報道可能與檸檬酸-蘋果酸鈣復(fù)合鹽的組成成分檸檬酸和蘋果酸是體內(nèi)三羧酸循環(huán) （TCA 循環(huán)）的中間代謝產(chǎn)物有關(guān)，隨著構(gòu)成檸檬酸-蘋果酸鈣復(fù)合鹽的檸檬酸和蘋果酸組分在體內(nèi)進入三羧酸循環(huán)參與代謝，而檸檬酸-蘋果酸鈣復(fù)合鹽緩慢地釋放鈣離子，從而提高了檸檬酸-蘋果酸鈣復(fù)合鹽的吸收利用性。

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Calcium Citrate Malate (CCM) is an organic chelate with spatial structure synthesized by calcium, citric acid and malic acid in a certain proportion, and the body has high absorption and utilization of calcium. Citric acid-calcium malate complex salt is an ideal calcium nutrient fortification agent with good solubility, high absorption and utilization, good flavor and so on. The absorption and utilization rate of calcium citrate malate was 37% higher than that of calcium carbonate. Animal tests also proved that the biological activity of calcium citrate malate was significantly higher than that of calcium carbonate, and the absorption, utilization and retention rate of calcium citrate malate were higher than that of calcium carbonate. It has been reported that the high absorption and utilization of citrate - calcium malate complex salt may be related to the fact that citrate and malic acid, the components of citrate - calcium malate complex salt, are intermediate metabolites of the tricarboxylic acid cycle (TCA cycle) in the body. As the citrate and malic acid components that constitute citrate - calcium malate complex salt enter the tricarboxylic acid cycle in the body and participate in metabolism, The citrate - calcium malate complex salt releases calcium ions slowly, which improves the absorption and utilization of citrate - calcium malate complex salt.