檸檬酸鋅(Zinc Citrate)的抗牙結(jié)石作用

牙結(jié)石是一種形成于自然牙面或牙修復體上黏附的、鈣化的或正在鈣化的團塊，通常是由牙菌斑鈣化形成的，其無機質(zhì)占70%～90%，主要有磷酸鈣75.9%，碳酸鈣3.1% 及少量其他物質(zhì)，有機質(zhì)為蛋白質(zhì)和類脂質(zhì)等。文獻研究表明檸檬酸鋅除了可以抑制牙菌斑外，其鋅離子能有效地緩解或減少牙結(jié)石的形成，可作用在磷酸鈣礦化過程中，具體過程分三方面: ①參與或干涉通常存在于牙結(jié)石中磷酸鈣晶體的形成; ②促進水溶解性更好的磷酸鈣鹽形成，如磷酸三鈣等; ③吸附在已經(jīng)生成的磷酸鈣晶面上，限制其進一步生長。有研究者發(fā)現(xiàn)鋅離子低濃度時可抑制二水合磷酸二鈣、磷酸三鈣等晶體的生長，高濃度時可幫助形成非晶態(tài)磷酸鈣和鋅取代的磷酸三鈣。多項臨床試驗也證實檸檬酸鋅牙膏能有效地抑制牙結(jié)石，如，Stephen 等人三年臨床實驗發(fā)現(xiàn)含0.5%三水合檸檬酸鋅牙膏與對照相比能顯著地抑制口腔牙結(jié)石。

檸檬酸鋅(Zinc Citrate)的抗牙結(jié)石作用

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L-谷氨酰胺L-Glutamine、L-異亮氨酸L-Isoleucine、L-色氨酸L-Tryptophan、甘氨酸銅Copper Glycinate、抗壞血酸鋅Zinc Ascorbate、吡啶甲酸鉻Chromium Picolinate、檸檬酸鉀Potassium Citrate、甘氨酸硼Boron Glycinate、氨基酸螯合硒Selenium Amino Acid Chelate、葡萄糖酸鎂Magnesium Gluconate

Anticalculus effect of Zinc Citrate

Dental calculus is a kind of calcified or calcifying mass formed on the natural tooth surface or dental prosthesis, usually formed by dental plaque calcification, the inorganic matter accounts for 70% to 90%, mainly calcium phosphate 75.9%, calcium carbonate 3.1% and a small number of other substances, the organic matter is protein and lipids. Literature studies have shown that in addition to inhibiting dental plaque, zinc citrate can effectively relieve or reduce the formation of dental stones, and can act in the process of calcium phosphate mineralization. The specific process is divided into three aspects: (1) participate in or interfere with the formation of calcium phosphate crystals, which usually exist in dental stones; (2) Promote the formation of calcium phosphate with better water solubility, such as tricalcium phosphate; (3) Adsorbed on the generated calcium phosphate crystal surface, limiting its further growth. Researchers have found that low concentrations of zinc ions can inhibit the growth of crystals such as dicalcium dihydrate and tricalcium phosphate, and high concentrations can help form amorphous calcium phosphate and zinc-replaced tricalcium phosphate. A number of clinical trials have also confirmed that zinc citrate toothpaste can effectively inhibit dental calculus. For example, Stephen et al. Stephen's three-year clinical trial found that toothpaste containing 0.5% zinc citrate trihydrate can significantly inhibit dental calculus compared with the control group.

Anticalculus effect of Zinc Citrate

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L-Glutamine；L-Isoleucine；L-Tryptophan；Copper Glycinate；Zinc Ascorbate；Chromium Picolinate；Potassium Citrate；Boron Glycinate；Selenium Amino Acid Chelate；Magnesium Gluconate；