葡萄糖酸鋅(Zinc Gluconate)治療輪狀病毒腹瀉患兒的有效性

輪狀病毒是一種引起腸胃疾病的常見(jiàn)病毒，其臨床危害性較大，具有分布廣以及傳染性高的特點(diǎn)，主要通過(guò)糞口傳播，可感染小腸上皮細(xì)胞，造成細(xì)胞損傷，從而引起腹瀉。嬰幼兒感染輪狀病毒引起腹瀉后，易造成腸道菌群失調(diào)，同時(shí)降低T淋巴細(xì)胞的免疫活性，導(dǎo)致患兒免疫調(diào)節(jié)功能出現(xiàn)障礙。目前，臨床上針對(duì)輪狀病毒腹瀉患兒的治療主要以抗感染以及防脫水為主，雖可緩解患兒的脫水癥狀及腹瀉癥狀，但由于輪狀病毒種類較多，大部分患兒治療后仍有機(jī)會(huì)受到感染，治療效果尚不顯著。鋅是人體必需的微量元素，其在人體生長(zhǎng)發(fā)育、生殖遺傳、免疫、內(nèi)分泌等重要生理過(guò)程中起著極其重要的作用。缺鋅容易導(dǎo)致生長(zhǎng)發(fā)育緩慢、消化及神經(jīng)功能下降以及免疫系統(tǒng)遭到破壞等不良影響，因此給予輪狀病毒腹瀉患兒補(bǔ)鋅可在一定程度上控制疾病。葡萄糖酸鋅中的鋅元素可以有效改善腸道菌群狀態(tài)，修復(fù)因輪狀病毒感染而損傷的腸道細(xì)胞，同時(shí)可促進(jìn)腸道細(xì)胞的生長(zhǎng)，從而提高患兒的抵抗力；鋅存在于碳酸酐酶、乳酸脫氫酶以及DNA和RNA聚合酶等之中，能夠促進(jìn)蛋白質(zhì)、核酸以及碳水化合物的合成，在提高患兒免疫功能上具有較強(qiáng)的促進(jìn)作用；此外，鋅能夠刺激腸黏膜對(duì)水以及鈉的吸收，控制水電解質(zhì)的分泌，從而改善患兒的脫水癥狀。因此，對(duì)于輪狀病毒腹瀉患兒而言，葡萄糖酸鋅是較為有效且安全性較高的治療藥物。

葡萄糖酸鋅(Zinc Gluconate)治療輪狀病毒腹瀉患兒的有效性

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甘氨酸亞鐵Ferrous Glycinate、天門冬氨酸鈣Calcium Aspartate、乳酸鋅Zinc Lactate、葡萄糖酸錳Manganese Gluconate、甘氨酸鎂Magnesium Glycinate、氨基酸螯合鉻Chromium Amino Acid Chelate、谷氨酸鋅Zinc Glutamate、蘇氨酸鎂Magnesium Threoninate、L-酪氨酸L-Tyrosine

The Effectiveness of Zinc Gluconate in Treating Children with Rotavirus Diarrhea

Rotavirus is a common virus that causes gastrointestinal diseases. It has great clinical harm, wide distribution and high infectivity. It is mainly transmitted through fecal mouth and can infect small intestinal epithelial cells, cause cell damage and cause diarrhea. After infantile infection with rotavirus caused diarrhea, it is easy to cause intestinal flora imbalance, and reduce the immune activity of T lymphocytes, resulting in immune regulation dysfunction in children. At present, clinical treatment for children with rotavirus diarrhea mainly focuses on anti-infection and anti-dehydration. Although the dehydration symptoms and diarrhea symptoms of children can be alleviated, most children still have the chance to be infected after treatment due to the large variety of rotavirus, and the therapeutic effect is not significant. Zinc is an essential trace element in human body, which plays an extremely important role in human growth and development, reproductive heredity, immunity, endocrine and other important physiological processes. Zinc deficiency is easy to lead to slow growth and development, digestive and nervous function decline and immune system damage and other adverse effects, so giving zinc supplementation to children with rotavirus diarrhea can control the disease to a certain extent. The zinc element in zinc gluconate can effectively improve the status of intestinal flora, repair intestinal cells damaged by rotavirus infection, and promote the growth of intestinal cells, thus improving the resistance of children. Zinc exists in carbonic anhydrase, lactate dehydrogenase and DNA and RNA polymerase, which can promote the synthesis of protein, nucleic acid and carbohydrate, and has a strong promoting effect on improving the immune function of children. In addition, zinc can stimulate the absorption of water and sodium by the intestinal mucosa and control the secretion of water and electrolytes, thereby improving the symptoms of dehydration in children. Therefore, zinc gluconate is an effective and safe treatment for children with rotavirus diarrhea.

The Effectiveness of Zinc Gluconate in Treating Children with Rotavirus Diarrhea

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Ferrous Glycinate；Calcium Aspartate；Zinc Lactate；Manganese Gluconate；Magnesium Glycinate；Chromium Amino Acid Chelate；Zinc Glutamate；Magnesium Threoninate；L-Tyrosine；